Description

2,2,2-Trifluoroethylhydrazine is a versatile fluorinated hydrazine derivative, a key building block in advanced organic synthesis. Its value lies in introducing the trifluoroethyl group and hydrazine functionality, enabling the creation of complex molecules with enhanced properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated heterocycles, active pharmaceutical ingredients (APIs), and potential drug candidates, leveraging the metabolic stability and lipophilicity imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve biological activity, environmental stability, and uptake in target organisms.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Polymer and Material Science: Employed in the synthesis of fluorinated polymers, resins, and specialty materials that require unique surface properties, chemical resistance, or thermal stability.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating fluorinated analogs of existing compounds.

Basic Information

Product Name	2,2,2-Trifluoroethylhydrazine
CAS No.	5042-30-8
Molecular Formula	C2H5F3N2
Molecular Weight	114.07 g/mol
Synonyms	2,2,2-Trifluoroethylhydrazine; 2,2,2-Trifluoroethanamine, N-amino-; 2,2,2-Trifluoroethyl Hydrazine; 1,1,1-Trifluoro-2-hydrozinoethane; 2,2,2-Trifluoro-1-hydrozinoethane; (2,2,2-Trifluoroethyl)hydrazine; Trifluoroethylhydrazine; Hydrazine, (2,2,2-trifluoroethyl)-
EINECS	225-730-9

Quality Control

Our 2,2,2-Trifluoroethylhydrazine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) in a sealed container. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.