Description

Methyl Tetra-o-Acetyl-α-D-Mannopyranoside is a key acetylated glycoside derivative, specifically the methyl glycoside of mannose where all hydroxyl groups are protected as acetate esters. This compound serves as a crucial protected intermediate in synthetic carbohydrate chemistry, enabling the controlled synthesis of complex oligosaccharides and glycoconjugates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel therapeutics, diagnostic agents, and advanced materials.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of complex carbohydrate-based drugs, including antiviral agents, antibiotics, and cancer therapeutics.
• Glycobiology Research: Used as a protected mannose donor in enzymatic and chemical glycosylation studies to investigate biological recognition processes.
• Oligosaccharide Synthesis: Serves as a key starting material for the stepwise construction of defined mannose-containing oligosaccharides and glycans.
• Glycoconjugate Production: Employed in the preparation of neoglycoconjugates for vaccine development and diagnostic assay applications.
• Chemical Biology Probes: Utilized to create labeled carbohydrate probes for studying protein-carbohydrate interactions and cell surface labeling.
• Fine Chemical Synthesis: Acts as a chiral precursor for the synthesis of specialty chemicals and advanced materials requiring specific sugar motifs.

Basic Information

Product Name	Methyl Tetra-o-Acetyl-α-D-Mannopyranoside
CAS No.	5019-24-9
Molecular Formula	C15H22O11
Molecular Weight	378.33 g/mol
Synonyms	Methyl 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranoside; Methyl α-D-Mannopyranoside Tetraacetate; 1-O-Methyl-2,3,4,6-tetra-O-acetyl-α-D-mannopyranose; α-Methyl-D-mannoside tetraacetate; Methyl α-D-Mannoside Tetraacetate; Tetra-O-acetyl-α-D-methylmannopyranoside; α-Methylmannopyranoside Tetraacetate
EINECS	225-695-5

Quality Control

Our Methyl Tetra-o-Acetyl-α-D-Mannopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.