Description

Ethyl Nipecotate is a versatile organic ester compound, serving as a crucial intermediate in advanced organic synthesis. Its value lies in its piperidine ring structure, which makes it a key building block for constructing complex molecules with significant biological activity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing the piperidine moiety, such as certain analgesics, antipsychotics, and nootropics.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides where the nipecotic acid derivative structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of complex flavor and fragrance compounds, dyes, and other specialty chemicals requiring a functionalized piperidine scaffold.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	Ethyl Nipecotate
CAS No.	5006-62-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	Ethyl Nipecotate; Ethyl 3-Piperidinecarboxylate; Nipecotic Acid Ethyl Ester; 3-Piperidinecarboxylic Acid, Ethyl Ester; Ethyl 3-Piperidinecarboxylate; NSC 404058; Ethyl Nipecotate (5006-62-2); Ethyl ester of nipecotic acid
EINECS	225-685-9

Quality Control

Our Ethyl Nipecotate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters such as assay (by GC/HPLC), identity confirmation (by IR/ NMR), and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.