Description

D-(-)-Pantolactone is the biologically active enantiomer of pantolactone, a key chiral intermediate in organic synthesis. Its high optical purity makes it essential for producing compounds with specific stereochemical requirements, ensuring efficacy and safety in final applications. This product is primarily required by manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for synthesizing active ingredients like D-pantothenic acid (Vitamin B5) and its derivatives.

Application

• Synthesis of D-pantothenic acid (Vitamin B5) and calcium pantothenate.
• Chiral building block for pharmaceutical active ingredients, including coenzyme A precursors.
• Intermediate in the production of cosmetics and personal care products.
• Manufacturing of animal feed additives and nutritional supplements.
• Key starting material for advanced fine chemicals and specialty polymers.
• Research and development of new bioactive molecules in academic and industrial labs.

Basic Information

Product Name	D-(-)-Pantolactone
CAS No.	599-04-2
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	(R)-(-)-Pantolactone; D-Pantolactone; (R)-Pantolactone; (R)-3-Hydroxy-4,4-dimethyl-dihydrofuran-2(3H)-one; (R)-4-Hydroxy-3,3-dimethyl-dihydro-2(3H)-furanone; (3R)-3-Hydroxy-4,4-dimethyloxolan-2-one; D-(-)-3-Hydroxy-4,4-dimethylbutyrolactone
EINECS	209-965-7

Quality Control

Our D-(-)-Pantolactone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, correct stereochemistry, and compliance with relevant standards for pharmaceutical and nutritional applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	-49° to -52° (c=1 in water)
Melting Point	90°C - 93°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.