Description

I-Propylisocyanide is a versatile organic building block and ligand, widely recognized for its utility in organometallic chemistry and synthetic applications. Its primary value lies in its role as a strong σ-donor ligand for transition metals, facilitating catalytic cycles and complex synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Catalysis & Ligand Chemistry: Acts as a strong σ-donor ligand in organometallic catalysis for coupling reactions and polymerization processes.
• Agrochemical Synthesis: Used in the production of specialized pesticides and herbicides requiring isocyanide-based chemistry.
• Material Science Research: Employed in the development of novel polymers, coordination polymers, and metal-organic frameworks (MOFs).
• Organic Synthesis: A crucial reagent in multi-component reactions, such as the Ugi and Passerini reactions, for creating diverse molecular libraries.
• Chemical Biology: Utilized in bioorthogonal chemistry and as a probe for labeling and studying biological systems.

Basic Information

Product Name	I-Propylisocyanide
CAS No.	598-45-8
Molecular Formula	C4H7N
Molecular Weight	69.11 g/mol
Synonyms	Isopropyl isocyanide; 2-Propyl isocyanide; Isocyanomethane, dimethyl-; (Dimethylmethyl)isocyanide; Isopropylisonitrile; 2-Propylisonitrile; Isocyanopropane; Isobutylisonitrile (common misnomer)
EINECS	209-935-8

Quality Control

Our I-Propylisocyanide is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and FTIR analysis, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for industrial and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, preferably at 2-8°C. Keep away from heat, sparks, and open flame. Containers should be kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~0.75 g/mL
Boiling Point	~90-92°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.