Description

Mannomustine is a nitrogen mustard derivative and a bifunctional alkylating agent with significant chemotherapeutic properties. This compound is valued for its ability to interfere with DNA replication and cell division, making it a critical intermediate in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of chemotherapeutic agents and other nitrogen mustard-based pharmaceuticals.
• Oncology Research: Used in biochemical and pharmacological studies to investigate alkylating mechanisms, cytotoxicity, and potential anti-cancer activities.
• Biochemical Tool: Employed as a model alkylating agent in laboratory studies of DNA damage, repair mechanisms, and cell cycle arrest.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Mannomustine
CAS No.	576-68-1
Molecular Formula	C10H19Cl2N3O5
Molecular Weight	332.18 g/mol
Synonyms	1,6-Bis(2-chloroethylamino)-1,6-dideoxy-D-mannitol; Degranol; BCM; Mannitol mustard; D-Mannitol, 1,6-bis(2-chloroethylamino)-1,6-dideoxy-; NSC-9698
EINECS	209-406-0

Quality Control

Our Mannomustine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC and NMR, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.