Description

Diethyl Acetylmalonate is a versatile organic ester and a key malonic acid derivative used as a high-value building block in fine chemical synthesis. Its primary value lies in its dual reactive sites, which enable its use as a precursor for heterocyclic compounds and complex molecular frameworks. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediates: A critical precursor in the synthesis of various heterocyclic compounds, including pyrimidines, pyridines, and barbiturates, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where it serves as a building block for creating complex molecules with specific biological activity.
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, dyes, and other specialty chemicals that require precise molecular architecture.
• Research & Development: A valuable reagent in academic and industrial R&D labs for methodological studies in organic synthesis and the development of new synthetic pathways.
• Coordination Chemistry: Can act as a ligand or precursor for ligands in metal-organic frameworks (MOFs) and catalytic systems due to its carbonyl and ester functional groups.

Basic Information

Product Name	Diethyl Acetylmalonate
CAS No.	570-08-1
Molecular Formula	C9H14O5
Molecular Weight	202.20 g/mol
Synonyms	Acetylmalonic Acid Diethyl Ester; Diethyl 2-Acetylmalonate; 2-Acetylmalonic Acid Diethyl Ester; Ethyl Acetylmalonate; Acetomalonic Ester; 1,3-Diethyl 2-Acetylpropanedioate; Propanedioic acid, acetyl-, diethyl ester; Acetylpropanedioic acid diethyl ester
EINECS	209-317-7

Quality Control

Every batch of Diethyl Acetylmalonate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	1.080 - 1.120 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.