Description

1,3,5(10)-Estratrien-3,17-β-Diol-16-One is a high-purity steroid derivative, specifically a key estrane intermediate. This compound is critical for the synthesis of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of steroidal drugs, reference standards, and advanced biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of steroidal hormones and related APIs.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for developing new therapeutic agents.
• Biochemical Studies: Employed in metabolic pathway research and studies involving steroid hormone action and biosynthesis.
• Fine Chemical Synthesis: Serves as a precursor for manufacturing specialized steroid derivatives with modified biological activity.

Basic Information

Product Name	1,3,5(10)-Estratrien-3,17-β-Diol-16-One
CAS No.	566-75-6
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	16-Oxoestradiol; 16-Ketoestradiol; 3,17β-Dihydroxy-1,3,5(10)-estratrien-16-one; Estra-1,3,5(10)-triene-3,17β-diol-16-one; 16-Oxo-E2; 16-Keto-E2; 16-Oxo-17β-estradiol
EINECS	209-296-2

Quality Control

Our 1,3,5(10)-Estratrien-3,17-β-Diol-16-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.