Description

Quinine Phosphate is a high-purity pharmaceutical-grade salt of the natural alkaloid quinine, known for its distinct bitter taste and therapeutic properties. This compound is critical for ensuring precise formulation and consistent efficacy in medicinal applications. It serves as a key active pharmaceutical ingredient (API) and analytical standard for manufacturers and research laboratories in the pharmaceutical, nutraceutical, and flavor industries.

Application

• Pharmaceutical API: Primary use as an antimalarial agent in prescription medications.
• Bittering Agent: Used in the food and beverage industry, particularly in tonic waters and bitter liqueurs.
• Analytical Reference Standard: Serves as a certified standard for quality control and research in analytical chemistry and pharmacology.
• Nutraceutical Preparations: Incorporated into dietary supplements for its historical use in supporting wellness.
• Chemical Synthesis: Acts as a chiral starting material or intermediate in the synthesis of more complex pharmaceutical compounds.
• Laboratory Research: Utilized in biochemical and pharmacological studies investigating its mechanism of action and potential new applications.

Basic Information

Product Name	Quinine Phosphate
CAS No.	549-60-0
Molecular Formula	C20H24N2O2 • 2H3PO4 • xH2O
Molecular Weight	548.46 g/mol (Anhydrous)
Synonyms	Quinine Acid Phosphate; Quinine Diphosphate; Quinine Phosphate (1:2); Quinine Bis(phosphate); Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, phosphate (1:2); NSC 52904; Quinine Phosphate Salt
EINECS	Contact for details

Quality Control

Our Quinine Phosphate is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs where applicable. Every batch undergoes comprehensive analytical testing for identity, purity, and potency. Certificates of Analysis (COA) documenting all critical parameters are provided to ensure full traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (TLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-245° to -258° (c = 2 in 0.1M HCl)
Loss on Drying	≤ 5.0%
Sulfated Ash	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.