Description

Clomethiazole is a heterocyclic organic compound with significant pharmacological activity. This versatile chemical intermediate is valued for its role in the synthesis of specialized active pharmaceutical ingredients (APIs) and for research applications in neuropharmacology. It is primarily sought by manufacturers in the pharmaceutical industry and by research institutions engaged in central nervous system (CNS) studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sedative and anticonvulsant APIs.
• Research & Development: Used in preclinical studies investigating GABAergic neurotransmission and mechanisms of action for CNS disorders.
• Chemical Synthesis: Serves as a precursor for the development of novel heterocyclic compounds with potential therapeutic value.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Clomethiazole
CAS No.	533-45-9
Molecular Formula	C6H8ClNS
Molecular Weight	161.65 g/mol
Synonyms	5-(2-Chloroethyl)-4-methylthiazole; Chlormethiazole; Heminevrin; Distraneurin; Clomethiazole Edisylate; CLX
EINECS	208-574-1

Quality Control

Our Clomethiazole is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC profiles, to support your regulatory and research requirements. The product meets specifications suitable for pharmaceutical intermediate and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.