Description

(E)-2',3,4,4',5'-Pentahydroxychalcone is a naturally occurring polyphenolic compound belonging to the chalcone subclass of flavonoids. This compound is valued for its significant biological activity, serving as a key intermediate in the biosynthesis of other flavonoids and as a promising candidate for research in health and wellness applications. It is primarily sought by manufacturers and research institutions in the pharmaceutical, nutraceutical, and cosmetic industries for product development and advanced biochemical studies.

Application

• Pharmaceutical Intermediates: Serves as a crucial building block for the synthesis of more complex flavonoid-based active pharmaceutical ingredients (APIs).
• Nutraceutical & Dietary Supplements: Used in the formulation of high-value supplements targeting antioxidant support and metabolic health due to its polyphenolic structure.
• Cosmetic & Skincare Actives: Incorporated into anti-aging and protective skincare formulations for its potential antioxidant and skin-brightening properties.
• Biochemical Research: Employed as a standard or investigational compound in studies related to oxidative stress, inflammation, and metabolic pathways.
• Functional Food & Beverage Fortification: Used to enhance the nutritional profile of health-focused food and beverage products.
• Natural Product Isolation & Standardization: Acts as a reference standard for the quality control and standardization of botanical extracts rich in chalcones.

Basic Information

Product Name	(E)-2',3,4,4',5'-Pentahydroxychalcone
CAS No.	526-12-5
Molecular Formula	C₁₅H₁₂O₆
Molecular Weight	288.25 g/mol
Synonyms	2',3,4,4',5'-Pentahydroxychalcone; 2',3,4,4',5'-Pentahydroxy-trans-chalcone; 1-(2,3,4-Trihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one; trans-2',3,4,4',5'-Pentahydroxychalcone; NSC 407347; Chalconaringenin; 3,4,2',4',5'-Pentahydroxychalcone
EINECS	Contact for details

Quality Control

Our (E)-2',3,4,4',5'-Pentahydroxychalcone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged exposure to air should be minimized. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.