Description

Estriol Succinate is a synthetic ester derivative of the natural estrogen hormone estriol, widely utilized as a key pharmaceutical intermediate. This compound is valued for its enhanced stability and bioavailability compared to the parent hormone, making it a critical building block in advanced hormone replacement therapies and other steroid-based pharmaceuticals. It is essential for manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring high-purity steroid intermediates for research, development, and commercial production.

Application

• Pharmaceutical Intermediate: Primary use as a key starting material or intermediate in the synthesis of steroidal active pharmaceutical ingredients (APIs), particularly for hormone therapies.
• Hormone Replacement Therapy (HRT): Used in the development and formulation of medications for managing menopausal symptoms and other estrogen-deficiency conditions.
• Research & Development: Serves as a standard or reagent in biochemical research for studying estrogen receptor activity, metabolic pathways, and drug discovery.
• Veterinary Pharmaceuticals: Employed in the formulation of hormonal treatments for animals.
• Cosmeceutical Ingredients: Potential use in the development of advanced skincare products targeting estrogen-related skin aging.

Basic Information

Product Name	Estriol Succinate
CAS No.	514-68-1
Molecular Formula	C22H28O6
Molecular Weight	388.46 g/mol
Synonyms	Estriol 16α,17β-Hemisuccinate; 16α,17β-Dihydroxyestra-1,3,5(10)-trien-3-yl hydrogen succinate; Estr-5(10)-ene-3,16α,17β-triol 16,17-Dihemisuccinate (mixed isomers); Estriol 16,17-Disuccinate; Oestriol Succinate; NSC 23162
EINECS	208-185-2

Quality Control

Our Estriol Succinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all test results are provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.