Description

1-Piperideine is a versatile, nitrogen-containing heterocyclic building block of significant importance in advanced organic synthesis. Its strained, cyclic imine structure makes it a valuable precursor for constructing complex piperidine-based frameworks, which are core motifs in numerous active pharmaceutical ingredients and agrochemicals. This high-purity intermediate is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active compounds or optimize synthetic routes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine alkaloids and a wide range of bioactive molecules, including potential CNS agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the piperidine scaffold contributes to biological activity.
• Fine Chemical Production: Serves as a building block for specialty chemicals, catalysts, and ligands used in asymmetric synthesis and material science.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, particularly in studies involving imine chemistry, cycloadditions, and heterocycle formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein-ligand interactions.

Basic Information

Product Name	1-Piperideine
CAS No.	505-18-0
Molecular Formula	C5H9N
Molecular Weight	83.13 g/mol
Synonyms	1-Piperideine; δ¹-Piperideine; 2,3,4,5-Tetrahydropyridine; 3,4,5,6-Tetrahydropyridine; 1,2,3,6-Tetrahydropyridine; 1-Piperidine; Piperideine; Tetrahydropyridine; Azacyclohex-1-ene
EINECS	208-001-3

Quality Control

Our 1-Piperideine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic and easily oxidized nature, containers should be kept sealed and allowed to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.