Description

Guaiaretic Acid is a naturally occurring lignan derivative, a dimeric compound formed from two coniferyl alcohol units. This compound serves as a valuable chemical intermediate and a reference standard for analytical and research purposes. It is primarily utilized by industries involved in the synthesis of pharmaceuticals, fine chemicals, and in life science research.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and analytical method development in laboratories.
• Biochemical Research: Employed in studies investigating lignan biosynthesis, antioxidant activity, and other biological pathways.
• Fine Chemical Synthesis: Acts as a key building block for the preparation of more complex organic molecules and specialty chemicals.
• Natural Product Isolation & Analysis: Used as a benchmark in the isolation, identification, and quantification of lignans from plant extracts.

Basic Information

Product Name	Guaiaretic Acid
CAS No.	500-40-3
Molecular Formula	C₂₀H₂₂O₆
Molecular Weight	358.39 g/mol
Synonyms	Nordihydroguaiaretic Acid (NDGA); 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]; meso-1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane; (±)-Nordihydroguaiaretic Acid; 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane; NSC 4291; Larrea acid
EINECS	207-903-0

Quality Control

Our Guaiaretic Acid is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data upon request, supporting its use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	184 - 188 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.