Description

3-Pyridinecarboxaldehyde is a versatile heterocyclic aldehyde building block essential for advanced organic synthesis. Its reactive formyl group makes it a critical precursor for constructing complex molecules in pharmaceutical and agrochemical research. This high-purity intermediate is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key starting material for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of nicotinic receptor modulators and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for pyridine-based ligands used in homogeneous catalysis and metal complexation.
• Chemical Research & Development: Fundamental building block for creating novel heterocyclic compounds, dyes, and functional materials.
• Cross-Coupling Reactions: Employed in palladium-catalyzed reactions like Suzuki-Miyaura and Stille couplings to introduce the pyridine-carboxaldehyde moiety.
• Condensation Reactions: Used in the synthesis of Schiff bases, imines, and other nitrogen-containing compounds for various industrial applications.

Basic Information

Product Name	3-Pyridinecarboxaldehyde
CAS No.	500-22-1
Molecular Formula	C6H5NO
Molecular Weight	107.11 g/mol
Synonyms	Nicotinaldehyde; Pyridine-3-carboxaldehyde; 3-Formylpyridine; 3-Pyridylaldehyde; 3-Pyridylcarboxaldehyde; m-Pyridinecarboxaldehyde; β-Pyridinecarboxaldehyde; NSC 4019
EINECS	207-896-2

Quality Control

Our 3-Pyridinecarboxaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and supplied with each order to meet the stringent documentation requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.