Description

Ethinyl Estradiol is a potent synthetic estrogen widely recognized for its critical role in pharmaceutical formulations. Its high biological activity and stability make it a cornerstone ingredient in modern hormone therapy. This compound is essential for manufacturers in the pharmaceutical industry, particularly for the production of oral contraceptives and hormone replacement therapies. We supply Ethinyl Estradiol CAS NO 57-63-6 to meet the stringent quality demands of global pharmaceutical applications.

Application

• Active Pharmaceutical Ingredient (API) in combined oral contraceptive pills.
• Hormone Replacement Therapy (HRT) for managing menopausal symptoms.
• Treatment for certain hormone-sensitive conditions, such as prostate cancer and advanced breast cancer.
• Research and Development of new endocrine-based therapeutics and drug delivery systems.
• Reference Standard in analytical laboratories for quality control and method validation.
• Veterinary Pharmaceuticals for reproductive management in animals.

Basic Information

Product Name	Ethinyl Estradiol
CAS No.	57-63-6
Molecular Formula	C20H24O2
Molecular Weight	296.40 g/mol
Synonyms	19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol; EE2; 17α-Ethynylestradiol; Ethynylestradiol; Lynoral; Estinyl; 17α-Ethinyl-1,3,5(10)-estratriene-3,17β-diol
EINECS	200-342-2

Quality Control

Our Ethinyl Estradiol is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Quality is verified through comprehensive analytical testing, including HPLC for assay and related substances, and IR for identification. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with in-house specifications. We can support compliance with major pharmacopoeial standards such as USP and EP upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.