Description

Isonicotinic Acid CAS NO 55-22-1 is a versatile heterocyclic carboxylic acid derivative of pyridine, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive carboxylic acid group and a nitrogen-containing heterocyclic ring, enabling its use in creating complex molecular architectures. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and material science industries, where it is used to synthesize active ingredients, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of important drugs, including first-line anti-tuberculosis agents like Isoniazid, and other medicinal compounds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, contributing to crop protection solutions.
• Ligand & Catalyst Preparation: Serves as a starting material for creating chelating ligands and organometallic catalysts used in homogeneous catalysis and material processing.
• Polymer & Material Science: Incorporated into polymer backbones to impart specific properties, such as metal coordination sites or enhanced thermal stability, for advanced materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and developing novel chemical entities.
• Coordination Chemistry: Acts as a versatile linker or building block in the construction of metal-organic frameworks (MOFs) and other coordination polymers.

Basic Information

Product Name	Isonicotinic Acid
CAS No.	55-22-1
Molecular Formula	C6H5NO2
Molecular Weight	123.11 g/mol
Synonyms	4-Pyridinecarboxylic Acid; γ-Picolinic Acid; 4-Carboxypyridine; Isonicotinsäure (German); Acide isonicotinique (French); p-Pyridinecarboxylic Acid; Pyridine-4-carboxylic Acid; 4-Pyridylcarboxylic Acid
EINECS	200-226-3

Quality Control

Our Isonicotinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the required specifications for purity, identity, and impurity profiles. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which are available for every shipment. Our quality commitment ensures reliability for your critical synthesis and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the product from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	310 - 315 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.