Description

Pipobroman CAS NO 54-91-1 is a synthetic alkylating agent belonging to the class of brominated piperidine derivatives. This compound serves as a critical active pharmaceutical ingredient (API) for the formulation of antineoplastic medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in oncology drug development and production. Our supply ensures high purity and consistent quality to meet stringent pharmacopeial standards.

Application

• Pharmaceutical API: Primary use as the active ingredient in chemotherapy drugs for the treatment of specific hematologic malignancies, such as polycythemia vera and essential thrombocythemia.
• Oncological Research: Utilized as a reference standard and biochemical tool in cancer research to study mechanisms of alkylation, DNA cross-linking, and cell cycle arrest.
• Drug Formulation: Serves as the key component in the development and manufacturing of oral dosage forms, including tablets and capsules.
• Clinical Trial Material: Supplied as a high-purity compound for use in preclinical studies and clinical trials for new cancer therapeutics.
• Analytical Standard: Used as a certified reference material (CRM) in quality control laboratories for HPLC, LC-MS, and other analytical method development and validation.

Basic Information

Item	Detail
Product Name	Pipobroman
CAS No.	54-91-1
Molecular Formula	C10H16Br2N2O2
Molecular Weight	356.06 g/mol
Synonyms	1,4-Bis(3-bromopropionyl)piperazine; Vercyte; Amedel; NSC-25154; Pipobromanum; 1,4-Bis(3-bromopropanoyl)piperazine; Pipobromane; UNII-8M7F6O0D3L
EINECS	200-220-3

Quality Control

Our Pipobroman is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets or exceeds relevant pharmacopeial standards (such as USP/EP monographs where applicable). A detailed Certificate of Analysis (COA) documenting purity, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.