Description

Metaraminol is a potent sympathomimetic amine and adrenergic receptor agonist, widely recognized for its vasopressor activity. This high-purity pharmaceutical intermediate is critical for ensuring the efficacy and safety of finished drug formulations. It is primarily required by manufacturers in the pharmaceutical industry for the synthesis of critical care medications, particularly those used to manage acute hypotensive states.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in injectable formulations for the treatment of severe hypotension and shock.
• Vasopressor Drug Synthesis: Key intermediate in the manufacturing of drugs that increase blood pressure by causing vasoconstriction.
• Critical Care Medicine: Essential for producing medications used in surgical settings, intensive care units (ICUs), and emergency medicine to maintain perfusion pressure.
• Research & Development: Used in pharmacological studies and the development of new adrenergic agents or cardiovascular therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.

Basic Information

Product Name	Metaraminol
CAS No.	54-49-9
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	Metaraminol; L-Metaraminol; (-)-Metaraminol; Aramine; Pressonex; 3-Hydroxy-α-((methylamino)methyl)benzyl alcohol; m-Hydroxy-norephedrine; α-(1-Aminoethyl)-3-hydroxybenzyl alcohol
EINECS	200-207-5

Quality Control

Our Metaraminol is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and chiral analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with relevant pharmacopeial guidelines (e.g., USP, EP) and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Optical Rotation	-30.0° to -34.0° (c=1 in H2O)
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.