Description

17-Desoxyestradiol is a key steroid intermediate and a derivative of estradiol, characterized by the absence of a hydroxyl group at the 17-position. This structural modification makes it a valuable building block in the synthesis of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of steroidal drugs and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of various steroidal drugs and hormonal therapies.
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and endocrinology research.
• API Development: Serves as a key building block for the research and development of new Active Pharmaceutical Ingredients (APIs) with modified biological activity.
• Steroid Chemistry: Employed in organic synthesis laboratories for creating novel steroid analogs and exploring structure-activity relationships (SAR).
• Analytical Standard: Used to calibrate equipment and validate methods in quality control (QC) laboratories for steroid analysis.

Basic Information

Product Name	17-Desoxyestradiol
CAS No.	53-63-4
Molecular Formula	C18H24O2
Molecular Weight	272.38 g/mol
Synonyms	Estra-1,3,5(10)-triene-3,17β-diol; 17-Deoxyestradiol; 3,17β-Dihydroxyestra-1,3,5(10)-triene; 17β-Estradiol-17-deoxy; Dihydroxyestratriene
EINECS	200-184-5

Quality Control

Our 17-Desoxyestradiol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other chromatographic techniques, to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.