Description

Mitotan CAS NO 53-19-0 is a synthetic derivative of the insecticide DDT, specifically developed for its adrenocorticolytic properties. This compound is of significant commercial and medical importance as a potent chemotherapeutic agent for the treatment of inoperable adrenocortical carcinoma. It is primarily required by the pharmaceutical industry for the formulation of specialty oncology drugs and is also utilized in biochemical research for studying adrenal cortex function and related endocrine pathways.

Application

• Oncological Pharmaceutical Manufacturing: Key active pharmaceutical ingredient (API) in medications for treating adrenocortical carcinoma.
• Biomedical Research: Used as a biochemical tool to study adrenal gland physiology, steroidogenesis, and cell apoptosis mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical labs and regulatory testing.
• Veterinary Medicine: Investigated for use in treating adrenal disorders in companion animals.
• Metabolic Studies: Employed in research focused on understanding the metabolic pathways and bioactivation of chemotherapeutic agents.

Basic Information

Product Name	Mitotan
CAS No.	53-19-0
Molecular Formula	C14H10Cl4
Molecular Weight	320.04 g/mol
Synonyms	o,p'-DDD; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; Lysodren; Chloditan; Chlonoditan; CB-313; NSC-38721; 2,4'-DDD
EINECS	200-170-6

Quality Control

Our Mitotan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Quality is verified through comprehensive analytical testing including HPLC, GC, and spectroscopic methods. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.