Description

Atropine Methyl Nitrate CAS NO 52-88-0 is a quaternary ammonium salt derivative of atropine, valued for its potent anticholinergic and antimuscarinic properties. This compound is critical for applications requiring precise control of smooth muscle activity and glandular secretions. It serves as an essential intermediate and active ingredient for the pharmaceutical, research, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key starting material or active pharmaceutical ingredient (API) in the synthesis of antispasmodic and antisecretory medications.
• Research Chemical: Used in pharmacological and biochemical research to study muscarinic acetylcholine receptor (mAChR) antagonism and related physiological pathways.
• Fine Chemical Synthesis: Employed as a building block in the preparation of more complex quaternary ammonium compounds and specialty chemicals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	Atropine Methyl Nitrate
CAS No.	52-88-0
Molecular Formula	C18H26N2O6
Molecular Weight	366.41 g/mol
Synonyms	Atropine Methonitrate; Atropine Methylnitrate; Methylatropine Nitrate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate methonitrate; Tropine tropate methonitrate; Eumydrin (historical trade name); Metanite
EINECS	200-158-5

Quality Control

Our Atropine Methyl Nitrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other pharmacopeial methods, to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to protect from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.