Description

Triethylenethiophosphoramide CAS NO 52-24-4 is a potent alkylating agent belonging to the class of aziridine derivatives. This compound is of significant commercial and research interest due to its role as a key intermediate in the synthesis of specialized polymers and as a model compound in biochemical studies. It is primarily sought by manufacturers in the pharmaceutical and advanced materials sectors for its reactive properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of specialized chemotherapeutic agents and other active pharmaceutical ingredients (APIs).
• Polymer Chemistry: Used as a cross-linking agent or monomer in the production of high-performance resins, coatings, and specialty polymers.
• Biochemical Research: Employed as a model alkylating agent in laboratory studies to investigate DNA interaction mechanisms and cytotoxicity.
• Chemical Synthesis: Acts as a versatile reagent for introducing the aziridine functional group into more complex organic molecules.
• Material Science: Utilized in the development of functionalized surfaces and advanced composite materials.

Basic Information

Product Name	Triethylenethiophosphoramide
CAS No.	52-24-4
Molecular Formula	C6H12N3PS
Molecular Weight	189.22 g/mol
Synonyms	TETP; ThioTEPA; Tri(1-aziridinyl)phosphine sulfide; N,N',N''-Triethylenethiophosphoramide; Tris(aziridin-1-yl)phosphine sulfide; 1,1',1''-Phosphinothioylidynetrisaziridine; TESPA; TSPA; NSC 6396
EINECS	200-120-5

Quality Control

Our Triethylenethiophosphoramide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.