Description

Atropine CAS NO 51-55-8 is a naturally occurring tropane alkaloid extracted from plants of the *Solanaceae* family, such as deadly nightshade. It is a potent, competitive antagonist of muscarinic acetylcholine receptors, making it a critical pharmaceutical active ingredient. This compound is essential for manufacturers in the pharmaceutical, research, and agrochemical sectors requiring a high-purity, reliable supply of this versatile active pharmaceutical ingredient (API).

Application

• Pharmaceutical API: Core ingredient in ophthalmic solutions for pupil dilation (mydriasis) and cycloplegia, as well as in pre-anesthetic medication to reduce secretions.
• Antidote Formulations: Used in auto-injectors and emergency kits for the treatment of poisoning by organophosphate nerve agents and pesticides.
• Cardiac Applications: Employed in the management of symptomatic bradycardia (slow heart rate) and certain types of heart block.
• Gastrointestinal Therapeutics: A component in antispasmodic medications for treating irritable bowel syndrome (IBS) and other gastrointestinal spasms.
• Veterinary Medicine: Used as a pre-anesthetic, for ophthalmic procedures, and as an antidote in animals.
• Biochemical Research: A standard muscarinic receptor antagonist used in pharmacological, neurological, and physiological studies.
• Agrochemical Reference Standard: Serves as a model compound and analytical standard in the development and testing of certain pesticides.

Basic Information

Product Name	Atropine
CAS No.	51-55-8
Molecular Formula	C17H23NO3
Molecular Weight	289.38 g/mol
Synonyms	dl-Hyoscyamine; Atropine Sulfate (salt form); (±)-Hyoscyamine; Tropine tropate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate; Daturine; Atropinol
EINECS	200-104-8

Quality Control

Our Atropine is produced and tested under strict quality management systems to meet the rigorous demands of pharmaceutical manufacturing. We offer grades compliant with USP, EP, and BP monographs, ensuring identity, purity, strength, and composition. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological quality. Our quality commitment extends to full traceability and documentation in line with cGMP principles.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The product is light-sensitive; ensure containers are opaque or stored in dark conditions. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder or colorless crystals
Identification (IR)	Conforms to standard
Identification (TLC)	Conforms to standard
Assay (HPLC)	98.5% - 101.0% (on dried basis)
Specific Optical Rotation	-0.50° to +0.50°
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.