Description

Norepinephrine is a critical endogenous catecholamine neurotransmitter and hormone, also known as noradrenaline. Its primary commercial value lies in its essential role as a high-purity active pharmaceutical ingredient (API) for life-saving medications. This compound is indispensable for the pharmaceutical industry, specifically in the formulation of injectable solutions used in emergency and critical care medicine to manage acute hypotension and cardiac arrest.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the treatment of severe hypotension, septic shock, and cardiac arrest.
• Critical Care Medicine: A key vasopressor agent administered in hospital emergency rooms, intensive care units (ICUs), and surgical settings to maintain blood pressure and organ perfusion.
• Research & Development: Used in biochemical and pharmacological research to study adrenergic receptors, neurotransmitter release, and cardiovascular physiology.
• Diagnostic Agent: Employed in certain diagnostic tests and clinical studies to assess autonomic nervous system function.
• Reference Standard: Serves as a high-purity analytical reference standard in quality control laboratories for HPLC, LC-MS, and other analytical methods.

Basic Information

Product Name	Norepinephrine
CAS No.	51-41-2
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	Noradrenaline; (R)-4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol; Levarterenol; Arterenol; L-Norepinephrine; (R)-Norepinephrine; 1-(3,4-Dihydroxyphenyl)-2-aminoethanol; Adrenor; Levophed
EINECS	200-096-6

Quality Control

Our Norepinephrine is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and compliance for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature, typically between 15°C and 25°C, in a dry environment. Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term stability. Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	-37.0° to -41.0° (c = 2 in 1N HCl)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.