Description

Pralidoxime Chloride is a quaternary ammonium oxime salt and a critical pharmaceutical active ingredient. It serves as a specific antidote for poisoning by organophosphate nerve agents and pesticides, functioning as a cholinesterase reactivator. This compound is essential for manufacturers in the pharmaceutical, research, and defense sectors developing emergency medical countermeasures and therapeutic formulations.

Application

• Active Pharmaceutical Ingredient (API) in antidote formulations for organophosphate poisoning.
• Key component in emergency medical kits and auto-injectors for military and first responder use.
• Research chemical for studying acetylcholinesterase inhibition and reactivation mechanisms.
• Reference standard in analytical laboratories for quality control of antidote products.
• Intermediate in the synthesis of more advanced oxime-based reactivators.
• Formulation into injectable solutions for clinical treatment of pesticide poisoning.

Basic Information

Product Name	Pralidoxime Chloride
CAS No.	51-15-0
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	2-PAM Chloride; Protopam Chloride; Pyridine-2-aldoxime methyl chloride; 2-Formyl-1-methylpyridinium chloride oxime; Pralidoxime Chloride (USP); 2-Hydroxyiminomethyl-1-methylpyridinium chloride; 1-Methyl-2-formylpyridinium chloride oxime; 2-Pyridine aldoxime methyl chloride
EINECS	200-076-8

Quality Control

Our Pralidoxime Chloride is manufactured under strict quality management systems. It is typically supplied to meet or exceed pharmaceutical-grade standards, with specifications aligned to relevant pharmacopoeial monographs. Comprehensive quality testing is performed, including assay, purity profiling, and identification. A Certificate of Analysis (COA) is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
pH (1% Solution)	3.5 - 5.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.