Description

Chloroquine Diphosphate CAS NO 50-63-5 is a well-established antimalarial and immunomodulatory agent belonging to the 4-aminoquinoline class. Its primary value lies in its proven efficacy against malaria parasites and its application in research for autoimmune conditions. This compound is essential for pharmaceutical manufacturers, research institutions, and laboratories developing therapeutic formulations. We supply high-purity grades to meet the stringent demands of global pharmaceutical production and advanced biomedical research.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of antimalarial medications.
• Biomedical Research: Used in in vitro and in vivo studies to investigate mechanisms of autophagy, immune response modulation, and viral replication inhibition.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmacopeial testing (e.g., USP, EP).
• Chemical Intermediate: Utilized in the synthesis of more complex chemical entities and derivatives for drug discovery programs.
• Veterinary Medicine: Employed in certain veterinary applications for protozoal infections.

Basic Information

Product Name	Chloroquine Diphosphate
CAS No.	50-63-5
Molecular Formula	C18H26ClN3 · 2H3PO4
Molecular Weight	515.86 g/mol
Synonyms	Chloroquine Phosphate; Chloroquine Bis(phosphate); 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline diphosphate; N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine diphosphate; SN 7618; Aralen Phosphate; Resochin; Tanakan
EINECS	200-055-2

Quality Control

Our Chloroquine Diphosphate is manufactured under strict quality management systems. Each batch is tested to ensure compliance with relevant pharmacopeial standards such as USP and EP, covering identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing all test results, including assay, related substances, and residual solvents, is provided with every shipment to guarantee traceability and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.