Description

Estradiol Benzoate is a potent, long-acting estrogen ester widely used in pharmaceutical and research applications. Its primary value lies in its enhanced stability and prolonged duration of action compared to unmodified estradiol, making it a critical component in various therapeutic formulations. This compound is essential for manufacturers in the pharmaceutical industry, veterinary medicine, and advanced life science research, particularly for hormone replacement therapies and reproductive health studies.

Application

• Pharmaceutical Active Ingredient (API): Core component in hormone replacement therapy (HRT) formulations for treating menopausal symptoms and estrogen deficiency.
• Veterinary Pharmaceuticals: Used in estrus synchronization and fertility treatments in livestock and companion animals.
• Research & Development: A standard reference compound in endocrinology, pharmacology, and toxicology studies investigating estrogenic activity.
• Controlled-Release Formulations: Employed in depot injections and implantable devices due to its esterified, lipophilic nature for sustained release.
• Biochemical Standard: Serves as a high-purity analytical standard for quality control and assay calibration in laboratory settings.

Basic Information

Product Name	Estradiol Benzoate
CAS No.	50-50-0
Molecular Formula	C25H28O3
Molecular Weight	376.49 g/mol
Synonyms	Estradiol 3-benzoate; Estradiol 17β-benzoate; Benzestrol; Benzoic acid estradiol ester; Oestradiol benzoate; Dimenformon benzoate; 17β-Estradiol 3-benzoate; (17β)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate
EINECS	200-043-7

Quality Control

Our Estradiol Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and melting point, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Melting Point	191°C - 196°C
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.