Description

Estriol is a naturally occurring estrogen steroid hormone, also known as oestriol, that plays a vital role in various physiological processes. As a key pharmaceutical intermediate and active pharmaceutical ingredient (API), it is essential for ensuring the quality and efficacy of hormone-based therapies. This high-purity compound is primarily sought by manufacturers in the pharmaceutical, biotechnology, and research sectors for the development and production of menopausal hormone replacement treatments, dermatological preparations, and diagnostic reagents.

Application

• Pharmaceutical API: Core active ingredient in hormone replacement therapy (HRT) medications for managing menopausal symptoms.
• Dermatological Formulations: Used in creams and ointments for treating vulvar and vaginal atrophy.
• Diagnostic Reagents: Serves as a standard or component in immunoassay kits for clinical hormone level testing.
• Biochemical Research: Critical reference standard and tool for studying estrogen receptor activity and endocrine function in laboratory settings.
• Veterinary Medicine: Employed in certain hormonal treatments for animals.
• Cosmeceutical R&D: Investigated for potential applications in anti-aging and skin health product development.

Basic Information

Product Name	Estriol
CAS No.	50-27-1
Molecular Formula	C18H24O3
Molecular Weight	288.38 g/mol
Synonyms	Oestriol; 1,3,5-Estratriene-3,16α,17β-triol; 16α-Hydroxyestradiol; Theelol; Trihydroxyestrin; E3; NSC 12169; Estra-1,3,5(10)-triene-3,16α,17β-triol
EINECS	200-022-8

Quality Control

Our Estriol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and specific tests for related substances and residual solvents, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting compliance with relevant standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.