Description

Cyclophosphamide is a potent nitrogen mustard alkylating agent and a cornerstone prodrug in the class of oxazaphosphorine cytostatics. Its primary value lies in its ability to interfere with DNA replication and cell division, making it a critical component in therapeutic regimens. This compound is essential for pharmaceutical manufacturers, research institutions, and compounding facilities developing oncology treatments, immunosuppressive therapies, and conducting biochemical research.

Application

• Oncological Therapeutics: A key active pharmaceutical ingredient (API) in the manufacture of chemotherapeutic drugs for treating various cancers, including lymphomas, leukemias, and solid tumors.
• Immunosuppression: Used in pharmaceutical preparations aimed at modulating the immune system, such as in treatments for severe autoimmune diseases and to prevent organ transplant rejection.
• Biomedical Research: Employed as a critical research chemical in preclinical and clinical studies to investigate mechanisms of alkylating agents, drug resistance, and novel combination therapies.
• Pharmaceutical Intermediates: Serves as a starting material or intermediate in the synthesis of more complex anticancer agents and related chemical entities.
• Reference Standard: Used in analytical laboratories as a high-purity standard for quality control (QC) and assurance (QA) testing of pharmaceutical products.

Basic Information

Item	Detail
Product Name	Cyclophosphamide
CAS No.	50-18-0
Molecular Formula	C7H15Cl2N2O2P
Molecular Weight	261.09 g/mol
Synonyms	Cyclophosphamide Monohydrate; 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide; CP; CPM; CY; Endoxan; Cytoxan; Neosar; Genoxal; Cycloblastin; Sendoxan; NSC-26271
EINECS	200-015-4

Quality Control

Our Cyclophosphamide is manufactured and tested under strict quality management systems. We ensure compliance with major pharmacopoeial standards, including USP and EP monographs, where applicable. Every batch is subjected to rigorous analytical testing for identity, purity, and impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. Ensure proper ventilation in the storage area and keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.