Description

Ethyl 3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-2-Carboxylate is a high-value heterocyclic building block and pharmaceutical intermediate with the CAS number 499787-31-4. This compound is critical for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used as a core structure for constructing libraries of novel compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the fused pyrido-oxazine moiety into target molecules.
• Research & Development (R&D): Essential for academic and industrial research laboratories focusing on heterocyclic chemistry and new therapeutic agent discovery.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Ethyl 3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-2-Carboxylate
CAS No.	499787-31-4
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	Ethyl 3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxylate; 2H-Pyrido[3,2-b][1,4]oxazine-2-carboxylic acid, 3,4-dihydro-, ethyl ester; Ethyl 2,3-dihydropyrido[3,2-b][1,4]oxazine-2-carboxylate; 499787-31-4; Ethyl 3,4-dihydro-2H-pyrido[3,2-b]-1,4-oxazine-2-carboxylate; SCHEMBL2180557; AKOS040759232; ZINC19764295
EINECS	Contact for details

Quality Control

Our Ethyl 3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging away from direct light and moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.