Description

1-Benzofuran-5-Yl Isocyanate is a specialized aromatic isocyanate building block used in advanced organic synthesis. This compound is valued for its reactive isocyanate group, which enables the efficient construction of ureas, carbamates, and other heterocyclic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drug candidates, particularly in kinase inhibitor and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for synthesizing polyurethanes, polyureas, and other specialty polymers with tailored properties.
• Chemical Biology & Proteomics: Employed as a labeling reagent or probe for modifying proteins and studying biological pathways.
• Liquid Crystal & OLED Material Development: Incorporated into the backbone of organic semiconductors and display materials to modify electronic and optical characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	1-Benzofuran-5-Yl Isocyanate
CAS No.	499770-79-5
Molecular Formula	C9H5NO2
Molecular Weight	159.14 g/mol
Synonyms	5-Isocyanatobenzofuran; 5-Isocyanato-1-benzofuran; Benzofuran-5-yl isocyanate; 1-Benzofuran-5-isocyanate; 5-Benzofuranyl isocyanate; Isocyanic acid, 1-benzofuran-5-yl ester; 499770-79-5
EINECS	Contact for details

Quality Control

Our 1-Benzofuran-5-Yl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and sources of ignition. Keep container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.