Description

Pritumumab is a human monoclonal antibody targeting a specific vimentin isoform expressed on the surface of certain tumor cells. This targeted therapeutic approach is significant for its potential in cancer immunotherapy, offering a mechanism to selectively bind to and neutralize malignant cells. It is primarily needed by pharmaceutical research and development teams, biopharmaceutical manufacturers, and clinical research organizations focused on advancing novel oncology treatments. The compound is identified by CAS No. 499212-74-7.

Application

• Primary research and development of novel monoclonal antibody-based cancer therapies.
• Pre-clinical and clinical studies investigating targeted immunotherapy for solid tumors, including brain cancer.
• Use as a reference standard in analytical method development and quality control for biopharmaceutical production.
• Investigational tool for studying cell surface vimentin's role in tumor biology and metastasis.
• Component in assay development for pharmacokinetic and pharmacodynamic studies.

Basic Information

Product Name	Pritumumab
CAS No.	499212-74-7
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Monoclonal Antibody)
Synonyms	NSC 732295; Human Anti-Vimentin Monoclonal Antibody; PCT-001; Monoclonal Antibody Pritumumab; Anti-Cell Surface Vimentin Antibody; CSVT mAb; Vimentin-targeting mAb
EINECS	Contact for details

Quality Control

Our Pritumumab is produced and handled under stringent quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and consistency. Specifications are aligned with ICH guidelines for biopharmaceuticals, and a detailed Certificate of Analysis (COA) documenting purity (by HPLC/SEC), endotoxin levels, sterility, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SEC-HPLC)	Consistent with reference standard
Purity (SEC-HPLC)	≥ 95% Monomer
Protein Content (UV/A280)	As per COA
Endotoxin	< 1.0 EU/mg
Sterility	Sterile
Biological Activity (Binding)	As per COA
Moisture Content (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.