Description

2,2-Dimethyl-n-(3-Trimethylsilanylethynyl-Pyridin-2-Yl)-Propionamide is a specialized organosilicon compound featuring a pyridine core and an alkyne-protected silyl group. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for the development of complex molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides with enhanced efficacy.
• Material Science Research: Serves as a functional monomer or cross-linking agent in the development of specialty polymers and silicon-based materials.
• Chemical Biology Probes: Employed in the creation of labeled compounds and probes for studying biological systems and mechanisms.
• Catalyst Ligand Development: The pyridine and silyl alkyne functionalities make it a candidate for designing novel ligands in transition metal catalysis.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	2,2-Dimethyl-n-(3-Trimethylsilanylethynyl-Pyridin-2-Yl)-Propionamide
CAS No.	499193-46-3
Molecular Formula	C15H22N2OSi
Molecular Weight	274.44 g/mol
Synonyms	N-(3-((Trimethylsilyl)ethynyl)pyridin-2-yl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-[3-(2-trimethylsilylethynyl)-2-pyridyl]propanamide; 2,2-Dimethyl-N-(3-((trimethylsilyl)ethynyl)pyridin-2-yl)propanamide; Propanamide, 2,2-dimethyl-N-[3-[2-(trimethylsilyl)ethynyl]-2-pyridinyl]-; TMS-protected pyridine alkyne amide; 3-((Trimethylsilyl)ethynyl)-N-(tert-butyl)pyridin-2-amine derivative
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-n-(3-Trimethylsilanylethynyl-Pyridin-2-Yl)-Propionamide adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.