Description

Pyridine, 3-(3-Pyrrolidinyl)-, (+)- (9Ci) is a chiral, nitrogen-containing heterocyclic compound that serves as a sophisticated building block in advanced organic synthesis. Its unique stereochemistry and functionalized pyridine-pyrrolidine scaffold make it a high-value intermediate for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical R&D and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for metal-catalyzed asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Employed in the synthesis of advanced, biologically active molecules for crop protection and pest management.
• Material Science: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry within academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Pyridine, 3-(3-Pyrrolidinyl)-, (+)- (9Ci)
CAS No.	498548-11-1
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(+)-3-(3-Pyrrolidinyl)pyridine; (R)-3-(Pyrrolidin-3-yl)pyridine; 3-[(3R)-Pyrrolidin-3-yl]pyridine; (R)-3-Pyridin-3-ylpyrrolidine; 3-(3-Pyrrolidinyl)pyridine, (R)-; (R)-Nornicotine (related structure); Pyrrolidin-3-yl-pyridine; (R)-3-(3-Pyridyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific analytical results, including chiral purity by HPLC, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.