Description

(E)-Ethyl 2-Oxo-4-(Pyridin-4-Yl)But-3-Enoate is a high-purity, synthetic organic compound featuring a conjugated enone system linked to a pyridine moiety, making it a versatile building block for advanced chemical synthesis. This compound is valued for its precise molecular structure, which is critical for developing complex molecules with specific electronic and steric properties. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and inflammatory pathways.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and organic electronic materials.
• Chemical Synthesis: Functions as a Michael acceptor or a dienophile in advanced organic synthesis, enabling the construction of complex heterocyclic frameworks.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	(E)-Ethyl 2-Oxo-4-(Pyridin-4-Yl)But-3-Enoate
CAS No.	497265-22-2
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	Ethyl (2E)-2-oxo-4-(4-pyridinyl)-3-butenoate; (E)-Ethyl 2-oxo-4-(pyridin-4-yl)but-3-enoate; 4-Pyridylacrylic acid ethyl ester, 2-oxo-; 2-Butenoic acid, 2-oxo-4-(4-pyridinyl)-, ethyl ester, (E)-; Ethyl 2-oxo-4-(4-pyridinyl)-2-butenoate; Ethyl (E)-2-oxo-4-(4-pyridinyl)-3-butenoate; 497265-22-2
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 2-Oxo-4-(Pyridin-4-Yl)But-3-Enoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.