Description

2H-Pyran,2-Ethoxy-3,4-Dihydro-4-(1-Methylethyl)-,(2S,4R)-(9Ci) is a chiral, substituted dihydropyran derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-value chiral building block for constructing complex molecular architectures with precise stereochemistry. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and the synthesis of natural products.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring specific stereocenters.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce the 2S,4R stereochemistry into target molecules.
• Natural Product Synthesis: Acts as a building block for the total or semi-synthesis of complex natural products containing dihydropyran or tetrahydropyran ring systems.
• Flavor & Fragrance Chemistry: Potential intermediate for the synthesis of sophisticated aroma chemicals and flavorants due to its oxygenated heterocyclic structure.
• Agrochemical Research: Employed in the discovery and development of novel chiral agrochemicals, such as herbicides or insecticides, where stereochemistry affects bioactivity.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	2H-Pyran,2-Ethoxy-3,4-Dihydro-4-(1-Methylethyl)-,(2S,4R)-(9Ci)
CAS No.	497161-63-4
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(2S,4R)-2-Ethoxy-4-isopropyl-3,4-dihydro-2H-pyran; 4-Isopropyl-2-ethoxy-3,4-dihydro-2H-pyran, (2S,4R)-; 2-Ethoxy-4-(1-methylethyl)-3,4-dihydro-2H-pyran, (2S,4R)-; (2S,4R)-4-Isopropyl-2-ethoxy-3,4-dihydro-2H-pyran; 2-Ethoxy-4-isopropyl-3,4-dihydro-2H-pyran (stereoisomer); Dihydro-2H-pyran, 2-ethoxy-4-(1-methylethyl)-, (2S,4R)-; Chiral 2-ethoxy dihydropyran derivative; 497161-63-4
EINECS	Contact for details

Quality Control

Our chiral intermediates are produced under strict quality management to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC for chiral purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity (assay), chiral excess, and impurity profiles are provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.