Description

Di-tert-Butyl [5-Bromo-3-Methylpyridin-2-Yl]Imidodicarbonate is a high-purity, protected pyridine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core.
• Ligand & Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic electronic materials and advanced polymers where functionalized pyridine units are required.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Di-tert-Butyl [5-Bromo-3-Methylpyridin-2-Yl]Imidodicarbonate
CAS No.	497159-91-8
Molecular Formula	C15H21BrN2O4
Molecular Weight	373.24 g/mol
Synonyms	Di-tert-butyl (5-bromo-3-methylpyridin-2-yl)imidodicarbonate; 2,2-Di-tert-butoxycarbonylamino-5-bromo-3-methylpyridine; 5-Bromo-3-methylpyridine-2-carbamic acid di-tert-butyl ester; 2-((Bis(tert-butoxycarbonyl)amino)-5-bromo-3-methylpyridine; Di-tert-butyl N-(5-bromo-3-methyl-2-pyridinyl)imidodicarbonate; 5-Bromo-3-methyl-2-pyridyl bis(tert-butoxycarbonyl)amine; Boc-protected 5-bromo-3-methyl-2-aminopyridine derivative
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl [5-Bromo-3-Methylpyridin-2-Yl]Imidodicarbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.