Description

1,3-Dioxo-n-(4-Pyridinyl)-2-(Tetrahydro-2-Furanylmethyl)-5-Isoindolinecarboxamide CAS NO 497062-81-4 is a high-purity, complex heterocyclic organic compound featuring a fused isoindoline core. This molecule is of significant interest in advanced pharmaceutical research and development, particularly as a sophisticated chemical intermediate or a potential pharmacophore. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and the development of new therapeutic agents. Its unique structure makes it a valuable building block for medicinal chemistry programs targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates and complex active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for investigating specific enzyme or receptor interactions in life science research.
• Organic Synthesis: Serves as a specialized intermediate for constructing complex polycyclic and heterocyclic frameworks in advanced synthetic chemistry.
• Contract Research & Development (CRO/CMO): Supplied to contract research and manufacturing organizations supporting pharmaceutical innovation.

Basic Information

Product Name	1,3-Dioxo-n-(4-Pyridinyl)-2-(Tetrahydro-2-Furanylmethyl)-5-Isoindolinecarboxamide
CAS No.	497062-81-4
Molecular Formula	C19H17N3O4
Molecular Weight	351.36 g/mol
Synonyms	5-Isoindolinecarboxamide, 1,3-dioxo-N-4-pyridinyl-2-(tetrahydro-2-furanylmethyl)-; 2-[(Tetrahydrofuran-2-yl)methyl]-N-(pyridin-4-yl)-1H-isoindole-4,6-dione-5-carboxamide; N-(4-Pyridyl)-2-(tetrahydrofurfuryl)-1,3-dioxoisoindoline-5-carboxamide; 497062-81-4; Tetrahydrofurfuryl-substituted isoindolinedione carboxamide; Pyridinyl isoindolinecarboxamide derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxo-n-(4-Pyridinyl)-2-(Tetrahydro-2-Furanylmethyl)-5-Isoindolinecarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.