Description

1-(4-Trimethylsilylphenyl)Piperazine is a high-value organosilicon-substituted piperazine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a piperazine ring and a trimethylsilyl-protected phenyl group, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used to construct complex molecules for next-generation pesticides and herbicides.
• Ligand Synthesis: Serves as a backbone for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and silicon-containing functional materials.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic pathways.
• Protecting Group Strategy: The trimethylsilyl group can be utilized in multi-step synthesis for selective protection and deprotection.

Basic Information

Product Name	1-(4-Trimethylsilylphenyl)Piperazine
CAS No.	496808-09-4
Molecular Formula	C13H22N2Si
Molecular Weight	234.41 g/mol
Synonyms	1-[4-(Trimethylsilyl)phenyl]piperazine; 4-(Piperazin-1-yl)phenyltrimethylsilane; 1-(4-Trimethylsilylphenyl)piperazine; 4-(Trimethylsilyl)phenylpiperazine; N-(4-Trimethylsilylphenyl)piperazine; 4-Piperazin-1-yl(trimethylsilyl)benzene; (4-Piperazin-1-ylphenyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our 1-(4-Trimethylsilylphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.