Description

2-(1,3-Benzoxazol-2-Yl)-3-(3,4-Dimethoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex chalcone-benzoxazole hybrid structure. This compound is of significant commercial interest for its role in the synthesis of novel bioactive molecules targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery of new chemical entities for oncology and neurological disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for kinase inhibitors and anti-cancer agents.
• Organic Light-Emitting Diode (OLED) Research: Serves as a potential electron-transporting or emissive layer material due to its conjugated benzoxazole core and methoxy-substituted aromatic systems.
• Agrochemical Research: Used in the development of new-generation pesticides and fungicides, leveraging its heterocyclic structure for biological activity.
• Fluorescent Probe Synthesis: Acts as a precursor for creating sensitive fluorescent dyes and molecular probes used in bioimaging and diagnostic assays.
• Material Science: Investigated as a monomer or additive for advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for fundamental studies in medicinal chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	2-(1,3-Benzoxazol-2-Yl)-3-(3,4-Dimethoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One
CAS No.	496011-81-5
Molecular Formula	C27H25NO7
Molecular Weight	475.49 g/mol
Synonyms	1-(3,4,5-Trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-2-(benzoxazol-2-yl)prop-2-en-1-one; (E)-2-(Benzoxazol-2-yl)-1-(3,4,5-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one; Chalcone-benzoxazole derivative; 2-Propen-1-one, 2-(1,3-benzoxazol-2-yl)-3-(3,4-dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-; Benzoxazolyl chalcone derivative; 496011-81-5; AGN-PC-0E7QJ7
EINECS	Contact for details

Quality Control

Our 2-(1,3-Benzoxazol-2-Yl)-3-(3,4-Dimethoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.