Description

Ethanone, 2-Chloro-1-([1,2,3]Thiadiazolo[5,4-B]Pyridin-6-Yl)- (9Ci) is a high-purity, advanced heterocyclic building block of significant interest in modern synthetic chemistry. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused thiadiazolopyridine core enables the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fused heterocyclic scaffolds.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	Ethanone, 2-Chloro-1-([1,2,3]Thiadiazolo[5,4-B]Pyridin-6-Yl)- (9Ci)
CAS No.	495416-05-2
Molecular Formula	C8H4ClN3OS
Molecular Weight	225.65 g/mol
Synonyms	2-Chloro-1-([1,2,3]thiadiazolo[5,4-b]pyridin-6-yl)ethanone; 6-Acetyl-2-chloro[1,2,3]thiadiazolo[5,4-b]pyridine; 2-Chloro-1-(thiadiazolo[5,4-b]pyridin-6-yl)ethan-1-one; 495416-05-2; [1,2,3]Thiadiazolo[5,4-b]pyridine, 6-acetyl-2-chloro-; Ethanone, 2-chloro-1-([1,2,3]thiadiazolo[5,4-b]pyridin-6-yl)-
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2-Chloro-1-([1,2,3]Thiadiazolo[5,4-B]Pyridin-6-Yl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.