Description

Saroglitazar is a novel, potent, and selective dual peroxisome proliferator-activated receptor (PPAR) agonist, primarily targeting the alpha and gamma subtypes. This compound is of significant interest for its therapeutic potential in managing metabolic disorders. It is particularly relevant for pharmaceutical research and development entities focused on cardiometabolic diseases. The material is supplied as a high-purity reference standard and active pharmaceutical ingredient (API) intermediate.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of finished drug products.
• Metabolic Disease Research: A key tool for in-vitro and in-vivo studies targeting non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and type 2 diabetes.
• Preclinical & Clinical Development: Employed in pharmacological and toxicological studies to support regulatory filings.
• Mechanistic Studies: Used to investigate PPAR-mediated pathways and their role in lipid and glucose metabolism.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production.

Basic Information

Product Name	Saroglitazar
CAS No.	495399-09-2
Molecular Formula	C₃₀H₃₄N₂O₄
Molecular Weight	486.60 g/mol
Synonyms	Saroglitazar; 2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid; 2-Ethoxy-3-[4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]phenyl]propanoic acid; (±)-Saroglitazar; Lipaglyn (Brand Name); GLP-1/PPAR dual agonist (related class); BM 152054 (possible code); BM-152054
EINECS	Contact for details

Quality Control

Our Saroglitazar CAS NO 495399-09-2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support regulatory requirements with comprehensive documentation. Certificates of Analysis (COA) detailing purity, related substances, residual solvents, and other critical parameters are available for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.