Description

5-Bromo-2-(Tetrahydropyran-4-Yloxy)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine core linked to a tetrahydropyranyloxy moiety. This compound matters as a versatile and critical building block for medicinal chemists, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized compounds under cGMP or research-grade conditions.

Basic Information

Product Name	5-Bromo-2-(Tetrahydropyran-4-Yloxy)Pyridine
CAS No.	494772-07-5
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	5-Bromo-2-[(oxan-4-yl)oxy]pyridine; 2-(Tetrahydro-2H-pyran-4-yloxy)-5-bromopyridine; 5-Bromo-2-(tetrahydropyran-4-yloxy)pyridine; 5-Bromo-2-(tetrahydro-2H-pyran-4-yloxy)pyridine; 5-Bromo-2-(4-tetrahydropyranyloxy)pyridine; 5-Bromo-2-(THP-4-yloxy)pyridine; 494772-07-5
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Tetrahydropyran-4-Yloxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.