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5-Bromo-2-(Cyclopropylmethoxy)Pyridine CAS NO 494772-02-0
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CAS No.:494772-02-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Bromo-2-(cyclopropylmethoxy)pyridine is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. Its unique molecular structure, featuring a bromine substituent and a cyclopropylmethoxy side chain, makes it a critical synthon for constructing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
- Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
- Chemical Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyridine moiety into more complex structures.
- Material Science: Potential monomer or additive in the research of specialty polymers and functional materials.
- Academic & R&D: A valuable reagent for synthetic organic chemistry research in university and industrial laboratories.
Basic Information
| Product Name | 5-Bromo-2-(cyclopropylmethoxy)pyridine |
| CAS No. | 494772-02-0 |
| Molecular Formula | C9H10BrNO |
| Molecular Weight | 228.09 g/mol |
| Synonyms | 2-Bromo-5-(cyclopropylmethoxy)pyridine; 5-Bromo-2-(cyclopropylmethoxy)pyridine; Pyridine, 5-bromo-2-(cyclopropylmethoxy)-; 494772-02-0; 5-Br-2-CPM-pyridine |
| EINECS | Contact for details |
Quality Control
Our 5-Bromo-2-(cyclopropylmethoxy)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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