Description

5-Bromo-2-[(Tetrahydro-3-Furanyl)Oxy]Pyridine is a high-value brominated pyridine derivative featuring a tetrahydrofuran ether linkage, serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and ether functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Intermediate in the production of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific bromo-ether scaffold.

Basic Information

Item	Details
Product Name	5-Bromo-2-[(Tetrahydro-3-Furanyl)Oxy]Pyridine
CAS No.	494771-98-1
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	5-Bromo-2-(tetrahydrofuran-3-yloxy)pyridine; 2-(Tetrahydro-3-furanyloxy)-5-bromopyridine; 5-Bromo-2-(oxolan-3-yloxy)pyridine; 5-Bromo-2-(3-tetrahydrofuranyloxy)pyridine; 494771-98-1; 5-Br-2-THPO-Pyridine; Bromopyridine tetrahydrofuran ether
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[(Tetrahydro-3-Furanyl)Oxy]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.