Description

n-Boc-4-Pyridine-2-Chloro-3-Ethanol is a protected amino alcohol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the orthogonal protection of the amine group by the Boc (tert-butoxycarbonyl) moiety, which allows for selective reactions at the alcohol and chloro-substituted pyridine ring. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and complex ligand systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides with pyridine-based core structures.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Peptide Mimetics: Employed in the construction of peptidomimetic scaffolds where the Boc-protected amine and alcohol functionalities are crucial.
• Material Science Research: A building block for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	n-Boc-4-Pyridine-2-Chloro-3-Ethanol
CAS No.	494767-21-4
Molecular Formula	C12H16ClNO3
Molecular Weight	257.71 g/mol
Synonyms	tert-Butyl (2-chloro-3-(hydroxymethyl)pyridin-4-yl)carbamate; 4-((tert-Butoxycarbonyl)amino)-2-chloro-3-pyridineethanol; 2-Chloro-3-(hydroxymethyl)-4-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; 4-(Boc-amino)-2-chloro-3-pyridineethanol; 2-Chloro-4-((tert-butoxycarbonyl)amino)pyridine-3-methanol; N-Boc-2-chloro-3-(hydroxymethyl)-4-aminopyridine; 4-Amino-2-chloro-3-pyridinemethanol N-Boc derivative; Boc-4-AP-2-Cl-3-EtOH
EINECS	Contact for details

Quality Control

Our n-Boc-4-Pyridine-2-Chloro-3-Ethanol undergoes rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.