Description

Piperidine, 4-Isocyanato-1-(Trifluoroacetyl)- (9Ci) is a specialized heterocyclic building block that combines a reactive isocyanate group with a trifluoroacetyl-protected piperidine scaffold. This molecular architecture makes it a critical intermediate for synthesizing advanced compounds with tailored properties. It is primarily sought after by pharmaceutical and agrochemical R&D teams for developing novel active ingredients, as well as by researchers in material science exploring functional polymers and advanced coatings.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polyurethanes, coatings, and adhesives with unique chemical resistance and performance characteristics.
• Chemical Research & Development: A versatile reagent for organic synthesis, enabling the introduction of both the isocyanate and protected amine functionalities in complex molecule construction.
• Ligand & Catalyst Development: Used to prepare novel ligands for catalysis or as a precursor for metal-organic frameworks (MOFs) and other advanced materials.

Basic Information

Product Name	Piperidine, 4-Isocyanato-1-(Trifluoroacetyl)- (9Ci)
CAS No.	493036-44-5
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	1-(Trifluoroacetyl)-4-isocyanatopiperidine; 4-Isocyanato-1-(trifluoroacetyl)piperidine; N-(Trifluoroacetyl)-4-isocyanatopiperidine; 1-(Trifluoroacetyl)piperidin-4-yl isocyanate; Piperidine-4-isocyanate, 1-trifluoroacetyl derivative; 4-Isocyanato-N-(trifluoroacetyl)piperidine
EINECS	Contact for details

Quality Control

Every batch of Piperidine, 4-Isocyanato-1-(Trifluoroacetyl)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development processes. A detailed Certificate of Analysis (COA) is available for each lot, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.