Description

Spiro[2.3]Hexane-1-Carboxamide, n-(3-Nitrophenyl)- (9Ci) is a specialized spirocyclic organic compound featuring a unique bridged ring structure and a nitro-substituted aromatic amide group. This molecular architecture makes it a valuable high-purity intermediate for advanced research and development in pharmaceutical and agrochemical synthesis. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly where a constrained, three-dimensional scaffold is required to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or insecticides that require complex, sterically defined molecular frameworks.
• Chemical Biology Probe: Acts as a scaffold for creating tool compounds to study enzyme function or protein-protein interactions in biological systems.
• Material Science Research: Potential monomer or precursor for synthesizing specialty polymers with unique thermal or mechanical properties.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies in organic synthesis and catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Spiro[2.3]Hexane-1-Carboxamide, n-(3-Nitrophenyl)- (9Ci)
CAS No.	491597-71-8
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	N-(3-Nitrophenyl)spiro[2.3]hexane-1-carboxamide; 1'-Carbamoylspiro[2.3]hexane-1-3'-nitrobenzene; Spiro[2.3]hexane-1-carboxylic acid (3-nitrophenyl)amide; 3-Nitro-N-(spiro[2.3]hexan-1-yl)benzamide; (3-Nitrophenyl)-amide of spiro[2.3]hexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of Spiro[2.3]Hexane-1-Carboxamide, n-(3-Nitrophenyl)- (9Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing including HPLC, NMR, and MS to ensure identity, purity, and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.