Description

1H-Imidazole-1-Aceticacid,α-Methylene-,Ethylester(9Ci) is a specialized heterocyclic building block with the CAS number 491080-00-3. This compound is valued for its reactive α-methylene ester group attached to the imidazole nitrogen, making it a versatile intermediate for synthesizing more complex molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole moiety is critical for binding.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and organometallic catalysts.
• Polymer Modification: Employed to introduce imidazole functionality into polymers, which can impart properties like metal coordination, pH-responsiveness, or biological activity.
• Chemical Biology Probes: Useful in the synthesis of probes and tags for studying biological processes due to the reactivity of the ester and the potential for further functionalization.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	1H-Imidazole-1-Aceticacid,α-Methylene-,Ethylester(9Ci)
CAS No.	491080-00-3
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	Ethyl 2-(imidazol-1-yl)acrylate; 1H-Imidazole-1-acetic acid, α-methylene-, ethyl ester; Ethyl (1H-imidazol-1-yl)acrylate; Ethyl 1H-imidazol-1-ylacrylate; α-Methylene-1H-imidazole-1-acetic acid ethyl ester; 2-(1H-Imidazol-1-yl)acrylic Acid Ethyl Ester; 1-(Ethoxycarbonylmethylene)imidazole
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-1-Aceticacid,α-Methylene-,Ethylester(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques, including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong bases and incompatible materials. For long-term storage, consider keeping the container under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.